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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC12A5
All Species:
23.94
Human Site:
Y926
Identified Species:
47.88
UniProt:
Q9H2X9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2X9
NP_001128243.1
1139
126184
Y926
S
D
I
S
A
Y
T
Y
E
K
T
L
V
M
E
Chimpanzee
Pan troglodytes
XP_001173480
1150
127612
R937
L
K
Q
H
K
V
W
R
K
C
S
I
R
I
F
Rhesus Macaque
Macaca mulatta
XP_001104798
1116
123517
Y903
S
D
I
S
A
Y
T
Y
E
K
T
L
V
M
E
Dog
Lupus familis
XP_543029
1042
114973
L841
D
G
G
M
L
M
L
L
P
F
L
L
R
H
H
Cat
Felis silvestris
Mouse
Mus musculus
Q91V14
1138
126252
Y926
S
D
I
S
A
Y
T
Y
E
K
T
L
V
M
E
Rat
Rattus norvegicus
Q63633
1139
126228
Y926
S
D
I
S
A
Y
T
Y
E
K
T
L
V
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506148
1141
126778
Y940
N
D
I
S
A
F
T
Y
E
K
T
L
V
M
E
Chicken
Gallus gallus
NP_001006371
1125
125222
Y920
N
D
I
S
A
F
T
Y
E
K
T
L
M
M
E
Frog
Xenopus laevis
Q0VGW6
899
98326
K698
S
M
I
C
D
A
L
K
M
H
K
N
I
V
L
Zebra Danio
Brachydanio rerio
A2BFP5
899
98457
D698
E
Y
V
S
I
I
Q
D
A
I
K
M
G
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09573
1020
112280
T819
A
V
S
E
Q
D
S
T
K
S
E
D
M
K
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38329
1120
123980
C913
T
N
R
I
D
T
P
C
E
S
E
D
S
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.6
96.1
88
N.A.
98.2
98.2
N.A.
72.1
73
24.6
25.2
N.A.
N.A.
N.A.
35.9
N.A.
Protein Similarity:
100
81
97
89.1
N.A.
98.6
98.8
N.A.
82.9
83.9
42.7
43.1
N.A.
N.A.
N.A.
54.8
N.A.
P-Site Identity:
100
0
100
6.6
N.A.
100
100
N.A.
86.6
80
13.3
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
26.6
100
6.6
N.A.
100
100
N.A.
100
100
26.6
20
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
50
9
0
0
9
0
0
0
0
0
9
% A
% Cys:
0
0
0
9
0
0
0
9
0
9
0
0
0
0
0
% C
% Asp:
9
50
0
0
17
9
0
9
0
0
0
17
0
9
0
% D
% Glu:
9
0
0
9
0
0
0
0
59
0
17
0
0
0
50
% E
% Phe:
0
0
0
0
0
17
0
0
0
9
0
0
0
0
9
% F
% Gly:
0
9
9
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
9
0
0
0
9
9
% H
% Ile:
0
0
59
9
9
9
0
0
0
9
0
9
9
9
0
% I
% Lys:
0
9
0
0
9
0
0
9
17
50
17
0
0
17
0
% K
% Leu:
9
0
0
0
9
0
17
9
0
0
9
59
0
0
17
% L
% Met:
0
9
0
9
0
9
0
0
9
0
0
9
17
50
0
% M
% Asn:
17
9
0
0
0
0
0
0
0
0
0
9
0
0
9
% N
% Pro:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
9
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
0
0
9
0
0
0
0
17
0
0
% R
% Ser:
42
0
9
59
0
0
9
0
0
17
9
0
9
0
0
% S
% Thr:
9
0
0
0
0
9
50
9
0
0
50
0
0
0
0
% T
% Val:
0
9
9
0
0
9
0
0
0
0
0
0
42
9
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
34
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _